Showing posts with label science. Show all posts
Showing posts with label science. Show all posts

Thursday, November 2, 2023

Brecht on Galileo on science


Bertolt Brecht composed his play Life of Galileo (1939) (link) while on the run in Denmark from Nazi Germany in 1938. Brecht was a determined anti-Nazi, and he was an advocate of revolutionary Marxism. It is fascinating to read one of the longest speeches he composed for Galileo at the end of the play, in which Galileo reflects on his recantation of the heliocentric theory of planetary motion. Rather than celebrating "pure science" over the oppression of the Church, Brecht has Galileo reflect bitterly on the corruption of science and its subservience to the powerful. This speech occurs in scene 14, near the end of the play. Galileo's disciple Andrea Sarti is interested in showing that Galileo's recantation was a wily move, allowing him to pursue the higher truths of science. And he is delighted to learn that Galileo has been secretly writing his Discorsi (Discourses and Mathematical Demonstrations Relating to Two New Sciences), which demonstrates to him that Galileo continues to pursue the highest values of science. Galileo disagrees, and offers a harsh criticism of the role of science in society altogether. The whole scene is worth reading carefully, but here is an important excerpt.
__________________________

A large room with table, leather chair and globe. Galileo, old now and half blind, is carefully experimenting with a bent wooden rail and a small ball of wood. In the antechamber sits a monk on guard. There is a knock on the door. The monk opens it and a peasant comes in carrying two plucked geese. Virginia emerges from the kitchen. She is now about forty years old.

...

Andrea: You gained the leisure to write a scientific work which could be written by nobody else. If you had ended up at the stake in a halo of flames the other side would have won.

Galileo: They did win. And there is no scientific work that can only be written by one particular man.

Andrea: Why did you recant, then?

Galileo: I recanted because I was afraid of physical pain.

Andrea: No!

Galileo: They showed me the instruments.

Andrea: So it wasn't planned?

Galileo: It was not.

Pause.

Andrea loudly: Science makes only one demand: contribution to science.

Galileo: And I met it. Welcome to the gutter, brother in science and cousin in betrayal! Do you eat fish? I have fish. [a] What stinks is not my fish but me. I sell out, you are a buyer. O irresistible glimpse of the book, the sacred commodity! The mouth waters and the curses drown. The great whore of Bablylon, the murderous beast, the scarlet woman, opens her thighs and everything is altered. Blessed be our horse-trading, whitewashing, death-fearing community!

Andrea: Fearing death is human. Human weaknesses don't matter to science.

Galileo: Don't they? -- My dear Sarti, even as I now am I think I can still give you a tip or two as to what matters to that science you have dedicated yourself to.

A short pause

Galileo professorially, folding his hands over his stomach:

In my spare time, of which I have plenty, I have gone over my case and considered how it is going to be judged by that world of science of which I no longer count myself a member. Even a wool merchant has not only to buy cheap and sell dear but also to ensure that the wool trade continues unimpeded. The pursuit of science seems to me to demand particular courage in this respect. It deals in knowledge procured through doubt. Creating knowledge for all about all, it aims to turn all of us into doubters. [b] Now the bulk of the population is kept by its princes, landlords, and priests in a pearly haze of superstition and old saws which cloak what these people are up to. The poverty of the many is as old as the hills, and from pulpit and lecture platform we hear that it is as hard as the hills to get rid of. Our new art of doubting delighted the mass audience. They tore the telescope out of our hands and trained it on their tormentors, the princes, landlords and priests. [c] These selfish and domineering men, having greedily exploited the fruits of science, found that the cold eye of science had been turned on a primaeval but contrived poverty that could clearly be swept away if they were swept away themselves. They showered us with threats and bribes, irresistible to feeble souls. But can we deny ourselves to the crowd and still remain scientists? [d] The movements of the heavenly bodies have become more comprehensible, but the peoples are as far as ever from calculating the moves of their rulers. The battle for a measurable heaven has been won thanks to doubt; but thanks to credulity the Rome housewife's battle for milk will be lost time and time again. Science, Sarti, is involved in both these battles. [e] A human race which shambles around in a pearly haze of superstition and old saws, too ignorant to develop its own powers, will never be able to develop those powers of nature which you people are revealing to it. To what end are you working? Presumably for the principle that science's sole aim must be to lighten the burden of human existence. [f] If the scientists, brought to heel by self-interested rulers, limit themselves to piling up knowledge for knowledge's sake, then science can be crippled and your new machines will lead to nothing but new impositions. You may in due course discover all that there is to discover, and your progress will nonetheless be nothing but a progress away from mankind. The gap between you and it may one day become so wide that your cry of triumph at some new achievement will be echoed by a universal cry of horror. -- As a scientist I had a unique opportunity. [g] In my day astronomy emerged into the market place. Given this unique situation, if one man had put up a fight it might have had tremendous repercussions. Had I stood firm the scientists could have developed something like the doctor's Hippocratic oath, a vow to use their knowledge exclusively for mankind's benefit. [h] As things are, the best that can be hoped for is a race of inventive dwarfs who can be hired for any purpose. What's more, Sarti, I have come to the conclusion that I was never in any real danger. For a few years I was as strong as the authorities. And I handed my knowledge to those in power for them to use, fail to use, misuse -- whatever best suited their objectives.

Virginia has entered with a dish and come to a standstill.

Galileo: I betrayed my profession. A man who does what I did cannot be tolerated in the ranks of science.

__________________________

What are the messages here about the relationship between science and society, between science and class? The view is unequivocal: science has been corrupted. Against the idealism offered by Sardi, Galileo asserts that science has come to serve the interests of the powerful, and it might have been different. Galileo's long speech here (plainly expressing Brecht's own social criticisms) offers a harsh and negative assessment of the role of science in society. And much of this speech derives, not from an unexpectedly radical sixteenth-century mathematician, but from the Marxist theories that Brecht had studied in the early 1930s.

[a] Galileo begins this diatribe with self-contempt. He looks at his work as a scientist as "selling out" -- offering the products of his intelligence and creativity for sale to the highest bidder. Science has been commodified, like the woolen-good trade. Galileo stinks like a rotten fish.

[b] Society is divided into rich and poor, powerful and powerless; and the rich and powerful dominate and exploit the poor and powerless. This fundamental reality is obscured by the "fog" of myth and misconception, or what Marx refers to as ideology. "Good" science can tear through the mystifications of popular beliefs and myths; but all too often the scientists refrain from providing the tools needed (the microscopes and telescopes) to penetrate the mists of common misconception about the social world.

[c] Science could have been a revolutionary force; it could have helped to "sweep away" the mystifications of the rich and powerful. Instead, the rich and powerful have bought and intimidated the scientists. The poor Roman housewife's quest for milk will be permanently difficult because the Roman proletariat has failed to see the necessity of sweeping away the class oppression of patrician and plebian social life.

[d] The point here is that Galileo has allowed human beings to see the real motions of the planets, but they still have not discovered the "laws of motion" of the social world. They continue to live in a world of illusions about how the social world works (like the Aristotelian or Ptolemaic conceptions of the planetary system). From Marx's Capital, Preface to the German Edition: "Intrinsically, it is not a question of the higher or lower degree of development of the social antagonisms that result from the natural laws of capitalist production. It is a question of these laws themselves, of these tendencies working with iron necessity towards inevitable results. The country that is more developed industrially only shows, to the less developed, the image of its own future."

[e] When ideology and mystification are allowed to persist, exploitation, domination, and poverty will persist as well.

[f] Science is distorted when it is put to service in the interests of the powerful. It no longer serves to benefit humanity, but rather only the landlords and the priests. And without science, ideology and mystification will continue to mislead the poor.

[g] Galileo seems to believe that the struggles with the Church over the Copernican Revolution during the Inquisition represented turning points for human emancipation, and there was a choice. Science could have become a permanent force for progress, or it could become a tool of enrichment for the powerful. Because scientists (including Galileo) lacked the courage to stand up, science became a tool of exploitation. The chance to orient science towards its own "Hippocratic oath" of allegiance to progress to humanity was lost.

[h] Here Galileo (Brecht) is contemptuous of scientists and inventors who do their work for commercial and monetary gain -- the smart people who put their imagination and intelligence to work for the highest bidder. And almost always the highest bidder is the exploiter -- the capitalist and the landlord who uses the products of science to enhance his wealth.

In this section of the play, then, Brecht breaks with a common narrative about the Galileo story: the pure and rational scientist who is forced to change his beliefs by an unthinking and authoritarian Church. In that story the scientist is the isolated individual courageously pursuing the truth for its own sake, and the Church is an authoritarian structure which is the antithesis of intellectual freedom. Instead, Brecht tells a more complicated story. It is not just the question of recanting "unacceptable" beliefs; it is the question of devoting one's scientific talents in service to the rich and powerful. Galileo's [Brecht's] fundamental critique is that "science" is allied with "the ruling class".


Friday, March 11, 2022

Advancing high-energy physics in the United States


Here is an interesting and important scientific question: where is high-energy physics going? What future discoveries are possible in the field? And what strategies are most likely to bring these breakthroughs about? HEP is the field of physics that studies sub-atomic particles -- muons, quarks, neutrinos, bosons, as well as now-familiar larger particles like neutrons, protons, and electrons -- and their interactions. Research in this field involves producing collisions of sub-atomic particles at high energies (speeds) to create conditions permitting observation of new particles and properties. (The image above is a screenshot of the breakthrough results achieved at Europe's CERN particle accelerator documenting observation of the Higgs boson.) And the most striking feature of HEP is the fact that it requires multi-billion-dollar tools (particle accelerators) and scientific teams (armies of advanced experimental physicists) to have any hope of making progress in the state of the field. Progress in high-energy physics does not happen in a garage or a university laboratory; it requires massive public investments in research facilities and scientific teams, organized around specific research objectives. In the United States these are largely located in the national laboratories (link) and through collaboration with international research facilities (CERN).

The question I want to address here is this: Who should be interested in a serious way in the topic of where research in high-energy physics is going? It should be emphasized that in this context I mean "interest" in a specific way: "materially, politically, or professionally concerned about the choices that are made". Who are the actors who contribute to setting the agenda for future scientific work in high-energy physics? To what extent do the scientists themselves determine the future of their scientific field? Is this primarily an academic and scientific question, a question of public policy, a question of national prestige, or possibly a question of economic growth and development?

One answer to "who should be interested" is straightforward and obvious: the small network of world-class experimental and theoretical physicists in the country whose scientific careers are devoted to progress and discovery in the field of high-energy physics. Every physicist who teaches physics in a university in a sense has an interest in the future of the field, and a small number of highly trained physicists have strong scientific intuitions about where future advances are most likely to be found. Moreover, there is only a relatively small number of expert physicists whose own abilities and the capacities of their laboratories have a realistic opportunity to contribute to progress in the field. So the expert scientific community, including experimental and theoretical physicists, computational experts, and instrumentation specialists, have highly informed ideas about where meaningful progress in physics is possible.

An institution with definite interest in the question is the formal organization that represents the collective scientific practice of American physics -- the American Physical Society (APS) (link). The APS is a prestigious organization which contributes specialized advice to government and the public on a range of questions, from the feasibility of anti-missile defense to the level of risk associated with global climate change (link).

An important practice involved directly in surveying the horizon for future physics advances is the Snowmass conference (link) (or more formally, the Particle Physics Community Planning Exercise). Snowmass is organized and managed by APS, and it has formal independence from the Department of Energy. Here is a thumbnail description of Snowmass:

The Particle Physics Community Planning Exercise (a.k.a. “Snowmass”) is organized by the Division of Particles and Fields (DPF) of the American Physical Society. Snowmass is a scientific study. It provides an opportunity for the entire particle physics community to come together to identify and document a scientific vision for the future of particle physics in the U.S. and its international partners. Snowmass will define the most important questions for the field of particle physics and identify promising opportunities to address them. (Learn more about the history and spirit of Snowmass here "How to Snowmass" written by Chris Quigg). The P5, Particle Physics Project Prioritization Panel, will take the scientific input from Snowmass and develop a strategic plan for U.S. particle physics that can be executed over a 10 year timescale, in the context of a 20-year global vision for the field. (link)

As noted, Snowmass is an arm of APS, with close informal ties to the Department of Energy and its advisory committee HEPAC. For this reason we would like to infer that it is a reasonably independent process, developing its assessments and recommendations based on the best scientific expertise and judgment available. But we can also ask whether it succeeds in the task of formulating a clear set of visions and priorities for the future of high-energy physics research, or instead presents a grab-bag of the particular views of its participating scientists. If the latter, does the Snowmass process succeed in influencing or guiding the decision-making that others will follow in setting priorities and budgets for future investments in physics research? So there is an important question for policy-institution analysis even at this early stage of our consideration: how "rational" is the Snowmass process, and how effective is it at distilling a credible scientific consensus about the future direction of high energy physics research? This is a question for policy studies in organizational sociology, similar to many studies in the field of science, technology, and society (STS).

Snowmass in turn plays into a more formal part of DoE's decision-making process, the P5 process (Particle Physics Project Prioritization Panel), which prepares a decennial report and strategic vision for the future of high-energy physics for the coming decade. This report is then conveyed to the DoE advisory committee and to DoE's director. (Here is a summary of the 2007-08 P5 report (link), and here is a link to the 2014 P5 report (link). In 2020 HEPAC conducted a review of the recommendations of the 2014 report and progress made towards those priorities (link).) Here too we can ask the organizational question: how effective is the P5 process at defining the best possible scientific consensus on priorities for the field of high energy physics research?

The National Academy of Sciences, Engineering and Medicine (link) is another organization that has an interest and capability in developing specific assessments and recommendations about the future of high-energy physics, and the research investments most likely to lead to important advances and discoveries. Here is a "consensus report" prepared by a group of leading physicists and commissioned by the NASEM Committee on Elementary Particle Physics in the 21st Century in 2006 (link).

Scientists are actors in the process of priority setting for the future of physics research, then. But it is clear that scientists do not ultimately make these decisions. Given that programs of research in high energy physics require multi-billion dollar investments, the Federal government is a major decision-maker in priority-setting for the future of physics. There are several Federal agencies that have a primary interest in setting the direction of future research in high-energy physics. The Department of Energy is the largest source of funding -- and therefore priorities -- for future investments in research in high-energy physics, including the neutrino detector DUNE project centered in Chicago at Fermilab and the now-defunct plan for the Superconducting Super Collider (SSC) in Texas in the 1980s, terminated in 1993. The Office of High Energy Physics (link) is ultimately responsible for decisions about major capital investments in this field, with budget oversight from Congressional committees. The Office of National Laboratories has oversight over the national laboratories (Fermilab, Argonne, Ames, Brookhaven, and several others). The DoE process is inherently agency-driven, given that it is concerned with a small number of highly impactful investment decisions. One such decision was the plan to implement the Deep Underground Neutrino Experiment (DUNE) at Fermilab in metro Chicago in around 2010 for several billion dollars. So here again we have an organizational problem for research: how are decisions made within the Office of High Energy Physics? Are the director and staff simply a transparent transmission belt from the physics community to DoE priorities? Or do agency officials have agendas of their own?

The Office of High Energy Physics is supported by an advisory committee of senior scientists, the High Energy Physics Advisory Committee (HEPAP). This committee exists to provide expert scientific advice to OHEP about priorities, goals, and scientific strategies. It is unclear whether HEPAP is enabled to fulfill this role given its current functioning and administration. Do members of HEPAP have the opportunity for free and open discussion of priorities and projects, or is the agenda of the committee effectively driven by OHEP director and staff?

Congress is an important actor in the formulation of science policy in general, and policy in the field of high-energy physics in particular, through its control of the Federal budget. Some elected officials also have an interest in the question in the future of physics, for a different reason. They believe that there are national interests at stake in the future developments of physics; and they believe that world-class scientific discovery and progress are important components of global prestige. Perhaps the US will be thought to be less of a scientific superpower than Japan or Europe in twenty years because the major advances in particle physics have taken place at CERN and advanced research installations in Japan. To maintain the edge, the elected official may have an interest in supporting budget decisions that boost the strength and effectiveness of US science -- including high-energy physics. Small investments guarantee minimal progress, whereas large investments make the possibility of significant breakthroughs much greater than would otherwise be the case.

There are still two constituencies to be considered: citizens and businesses. Do ordinary citizens have an interest in the future of high-energy physics? Probably not. No one has made the case for HEP that has been made for the planetary space program -- that research dollars spent on planetary space vehicles and exploration will lead to currently unpredictable but valuable technology breakthroughs that will "change daily life as we know it". No "teflon story" is likely to emerge from the DUNE project. HEP, neutrinos, hadron particles, and their like, as well as the accelerators, detectors, and computational equipment needed to evaluate their behavior, have little likelihood of leading to practical spin-off technologies. As a first approximation, then, ordinary citizens have little interest -- in either the economist's sense or the psychologist's sense -- in what strategies are likely to be most fruitful for the progress of high-energy physics.

The business community is different from the citizen and consumer segment for a familiar reason. Like citizens and consumers, business leaders have no inherent interest in the progress or future of high-energy physics. But as manufacturers of high-performance cryogenic electromagnet systems or instrumentation systems, they have a very distinct interest in supporting (and lobbying for) the establishment of major new technology-intensive infrastructure projects. This is similar to the defense industry; it is not that aircraft manufacturers want military conflict, but they recognize that building military aircraft is a profitable business strategy. So more military spending on high-tech weapons is better than less, from the point of view of defense contractors. The large cryogenic electromagnet producer has a very specific business interest in seeing an investment in a largescale neutrino experiment, because it will lead to expenditures in the range of hundreds of millions of dollars on electromagnets once construction begins.

Now that we've surveyed the players, what should we expect when it comes to science policy and strategy? Should we expect a highly rational process in which "scientific aims and goals" are debated and finalized by the scientific experts solicited by the American Physical Society and Snowmass; a report is received from the P5 process by the quasi-public body HEPAP that advises DoE on its strategies, and evaluated in a clear and rational basis; recommendations are conveyed to DoE officials, who introduce a note of budget realism but strive to craft a set of strategic goals for the coming decade that largely incorporate the wisdom of the APS/Snowmass report; DoE executives are able to make a compelling case for the public good to key legislators; and budget commitments are made to accomplish the top 5 out of 8 recommendations of the Snowmass report? Do we get a reasonably coherent and scientifically defensible set of strategies and investments out of this process?

The answer is likely to be clear to any social scientist. The clean lines of "recommendation, collection of expert scientific opinion, rational assessment, disinterested selection of priorities" will quickly be blurred by facts having to do with very well known organizational and political dysfunctions: conflicts of interest and agenda within agencies; industry and agency capture of the big-science agenda; conflicting interests among stakeholders; confusion within policy debates between longterm and medium-term objectives; imperfect communication within and across organizational lines; and a powerful interest expressed by local stakeholders to gain part of the benefits of the project as private incomes. It is illogical that parochial business interests in Chicago or Japan would influence the decision whether to fund the International Linear Collider (link); but this appears in fact to be the case. In other words, the clean and rational decision-making process we would like to see is broken apart by conflicts of interest and priority from various powerful actors. And the result may bear only a faint resemblance to the best judgments about "good science" that were offered by the scientific advisors in early stages of the process. March and Simon's "garbage can model" of organizational decision-making seems relevant here (link); or, as Charles Perrow describes the process in Complex Organizations (2014):

Goals may thus emerge in a rather fortuitous fashion, as when the organization seems to back into a new line of activity or into an external alliance in a fit of absentmindedness. (135)

No coherent, stable goal guided the total process, but after the fact a coherent stable goal was presumed to have been present. It would be unsettling to see it otherwise. (135)


Monday, April 20, 2020

The Malthusian problem for scientific research


It seems that there is a kind of inverse Malthusian structure to scientific research and knowledge. Topics for research and investigation multiply geometrically, while actual research and the creation of knowledge can only proceed in a selective and linear way. This is true in every field -- natural science, biology, social science, poetry. Take Darwin. He specialized in finches for a good while. But he could easily have taken up worms, beetles, or lizards, or he could have turned to conifers, oak trees, or cactuses. The evidence of speciation lies everywhere in the living world, and it is literally impossible for a generation of scientists of natural history to study them all.

Or consider a topic of current interest to me, the features that lead to dysfunctional performance in organizations large and small. Once we notice that the specific workings of an organization lead to harmful patterns that we care about a great deal, it makes sense to consider case studies of an unbounded number of organizations in every sector. How did the UAW work such that rampant corruption emerged? What features of the Chinese Communist Party led it to the profound secrecy tactics routinely practiced by its officials? What features of the Xerox Corporation made it unable to turn the mouse-based computer interface system into a commercial blockbuster? Each of these questions suggests the value of an organized case study, and surely we would learn a lot from each study. But each such study takes a person-year to complete, and a given scholar is unlikely to want to spend the rest of her career doing case studies like these. So the vast majority of such studies will never be undertaken. 

This observation has very intriguing implications for the nature of our knowledge about the world -- natural, biological, and social. It seems to imply that our knowledge of the world will always be radically incomplete, with vast volumes of research questions unaddressed and sources of empirical phenomena unexamined. We might take it as a premise that there is nothing in the world that cannot be understood if investigated scientifically; but these reflections suggest that we are still forced to conclude that there is a limitless range of phenomena that have not been investigated, and will never be.

It is possible that philosophers of physics would argue that this "incompleteness" result does not apply to the realm of physical phenomena, because physics is concerned to discover a small number of fundamental principles and laws about how the micro- and macro-worlds of physical phenomena work. The diversity of the physical world is then untroubling, because every domain of physics can be subsumed under these basic principles and theories. Theories of gravitation, subatomic particles and forces, space-time relativity, and the quantum nature of the world are obscure but general and simple, and there is at least the hope that we might arrive at a comprehensive physics with the resources needed to explain all physical phenomena, from black-hole pairs to the nature of dark matter.

Whatever the case with physics, the phenomena of the social world are plainly not regulated by a simple set of fundamental principles and laws. Rather, heterogeneity, exception, diversity, and human creativity are fundamental characteristics of the social world. And this implies the inherent incompleteness of social knowledge. Variation and heterogeneity are the rule; so novel cases are always available, and studying them always leads to new insights and knowledge. Therefore there are always domains of phenomena that have not yet been examined, understood, or explained. This conclusion is a bit like the diagonal proof of the existence of irrational numbers that drove Cantor mad: every number can be represented as an infinite decimal, and yet for every list of infinite decimals it is simple to generate another infinite decimal that is not on the list.

Further, in this respect it may seem that the biological realm resembles the social realm in these respects, so that biological science is inherently incomplete as well. Even granting that the theories of evolution and natural selection are fundamental and universal in biological systems, the principles specified in these theories guarantee diversification and variation in biological outcomes. As a result we might argue that the science of living systems too is inherently incomplete, with new areas of inquiry outstripping the ability of the scientific enterprise to investigate them. In a surprising way the uncertainties we confront in the Covid-19 crisis seem to illustrate this situation. We don't know whether this particular virus will stimulate an enduring immunity in individuals who have experienced the infection, and "first principles" in virology do not seem to afford a determinate answer to the question.

Consider these two patterns. The first is woven linen; the second is the pattern of habitat for invasive species across the United States. The weave of the linen is mechanical and regular; it covers all parts of the space with a grid of fiber. The second is the path-dependent result of invasion of habitat by multiple invasive species. Certain areas are intensively inhabited, while other areas are essentially free of invasive species. The regularity of the first image is a design feature of the process that created the fabric; the irregularity and variation of the second image is the consequence of multiple independent and somewhat stochastic yet opportunistic exploratory movements of the various species. Is scientific research more similar to the first pattern or the second?




I would suggest that scientific research more resembles the second process than the first. Researchers are guided by their scientific curiosity, the availability of research funding, and the assumptions about the importance of various topics embodied in their professions; and the result is a set of investigations and findings that are very intensive in some areas, while completely absent in other areas of the potential "knowledge space".

Is this a troubling finding? Only if one thought that the goal of science is to eventually provide an answer to every possible empirical question, and to provide a general basis for explaining everything. If, on the other hand, we believe that science is an open-ended process, and that the selection of research topics is subject to a great deal of social and personal contingency, then the incompleteness of science comes as no surprise. Science is always exploratory, and there is much to explore in human experience.

(Several earlier posts have addressed the question of defining the scope of the social sciences; link, link, link, link, link.)

Monday, August 3, 2015

Social construction of technical knowledge


After there was the sociology of knowledge (link), before there was a new sociology of knowledge (link), and more or less simultaneous with science and technology studies (link), there was Paul Rabinow's excellent ethnography of the invention of the key tool in recombinant DNA research -- PCR (polymerase chain reaction). Rabinow's monograph Making PCR: A Story of Biotechnology appeared in 1996, after the first fifteen years of the revolution in biotechnology, and it provides a profound narrative of the intertwinings of theoretical science, applied bench work, and material economic interests, leading to substantial but socially imprinted discoveries and the development of a powerful new technology. Here is how Rabinow frames the research:
Making PCR is an ethnographic account of the invention of PCR, the polymerase chain reaction (arguably the exemplary biotechnological invention to date), the milieu in which that invention took place (Cetus Corporation during the 1980s), and the key actors (scientists, technicians, and business people) who shaped the technology and the milieu and who were, in turn, shaped by them. (1)
This book focuses on the emergence of biotechnology, circa 1980, as a distinctive configuration of scientific, technical, cultural, social, economic, political, and legal elements, each of which had its own separate trajectory over the preceding decades. It examines the "style of life" or form of "life regulation" fashioned by the young scientists who chose to work in this new industry rather than pursue promising careers in the university world.... In sum, it shows how a contingently assembled practice emerged, composed of distinctive subjects, the site in which they worked, and the object they invented. (2)
There are several noteworthy features of these very exact descriptions of Rabinow's purposes. The work is ethnographic; it proceeds through careful observation, interaction, and documentation of the intentionality and practices of the participants in the process. It is focused on actors of different kinds -- scientists, lab technicians, lawyers, business executives, and others -- whose interests, practices, and goals are distinctly different from each others'. It is interested in accounting for how the "object" (PCR) came about, without any implication of technological or scientific inevitability. It highlights both contingency and heterogeneity in the process. The process of invention and development was a meandering one (contingency) and it involved a large group of heterogeneous influences (scientific, cultural, economic, ...).

Legal issues come into this account because the fundamental question -- what is PCR and who invented it? -- cannot be answered in narrowly technical or scientific terms. Instead, it was necessary to go through a process of practical bench-based development and patent law to finally be able to answer both questions.

A key part of Rabinow's ethnographic finding is that the social configuration and setting of the Cetus laboratory was itself a key part of the process leading to successful development of PCR. The fact of hierarchy in traditional scientific research spaces (universities) is common -- senior scientists at the top, junior technicians at the bottom. But Cetus had developed a local culture that was relatively un-hierarchical, and Rabinow believes this cultural feature was crucial to the success of the undertaking.
Cetus's organizational structure was less hierarchical and more interdisciplinary than that found in either corporate pharmaceutical or academic institutions. In a very short time younger scientists could take over major control of projects; there was neither the extended postdoc and tenure probationary period nor time-consuming academic activities such as committees, teaching, and advising to divert them from full-time research. (36)
And later:
Cetus had been run with a high degree of organizational flexibility during its first decade. The advantages of such flexibility were a generally good working environment and a large degree of autonomy for the scientists. The disadvantages were a continuing lack of overall direction that resulted in a dispersal of both financial and human resources and in continuing financial losses. (143)
A critical part of the successful development of PCR techniques in Rabinow's account was the highly skilled bench work of a group of lab technicians within the company (116 ff.). Ph.D. scientists and non-Ph.D. lab technicians collaborated well throughout the extended period during which the chemistry of PCR needed to be perfected; and Rabinow's suggestion is that neither group by itself could have succeeded.

So some key ingredients in this story are familiar from the current wisdom of tech companies like Google and FaceBook: let talented people follow their curiosity, use space (physical and social) to elicit strong positive collaboration; don't try to over-manage the process through a rigid authority structure.

But as Rabinow points out, Cetus was not an anarchic process of smart people discovering things. Priorities were established to govern research directions, and there were sustained efforts to align research productivity with revenue growth (almost always unsuccessful, it must be said). Here is Rabinow's concluding observation about the company and the knowledge environment:
Within a very short span of time some curious and wonderful reversals, orthogonal movements, began happening: the concept itself became an experimental system; the experimental system became a technique; the techniques became concepts. These rapidly developing variations and mutually referential changes of level were integrated into a research milieu, first at Cetus, then in other places, then, soon, in very many other places. These places began to resemble each other because people were building them to do so, but were often not identical. (169).
And, as other knowledge-intensive businesses from Visicalc to Xerox to H-P to Microsoft to Google have discovered, there is no magic formula for joining technical and scientific research to business success.



Sunday, September 7, 2014

Interests, influence and knowledge



Eric Lipton, Brooke Williams, and Nicholas Confessore have just published a major story in the New York Times on the topic of foreign influence on major think tanks (link), and through the think tanks, on American policy. It is a fascinating and important case study, and it deserves a broad and careful reading.

Here is a fascinating chart summarizing their findings that is included in the print version (but evidently not in the online version). The donor countries are classified by region, and it is possible to then inspect the rough volume of donation coming from each region to each foundation. Reading from right to left, it is possible to infer the regional focus of most of these institutes.


I find this story important for more general reasons than the particular relations and policies that it highlights. There is no smoking gun here, along the lines of a major tobacco company squelching scientific research into the harmful effects of smoking. It doesn't seem as though these think tanks have substantially breached the requirements of scientific integrity in negotiating funding and assigning research questions. More interesting to me is the light the piece sheds on the structures and sources of bias that exist in the institutions of science and policy formation.

The more general question is the causal significance of influence throughout the world of science and policy formation. We would like to think that important scientific questions like the rate of deforestation and policy areas like limits on Arctic development will be investigated by neutral and diligent scientists. We want their work to be independent and free from conflict of interest. But Lipton, Williams, and Confessore demonstrate that research institutions are susceptible to influence through their sources of funding, just as we have found that pharmaceutical research is often distorted by conflicts of interest. Righty understood, this piece falls within the domain of science studies (link, link).

Charles Perrow's important book, The Next Catastrophe: Reducing Our Vulnerabilities to Natural, Industrial, and Terrorist Disasters, points out similar forms of distortion in knowledge, science, and policy in the regulatory environment in the United States, including especially the Nuclear Regulatory Commission (link). Perrow makes it clear that both risk assessment and policy formation are significantly distorted by the economic interests and power of some of the actors involved.

If we think about the problem in a large epistemic frame, it is an exceptionally difficult one. There are important and difficult scientific questions to which we need to have answers as a society. These include estimating the acceptable risk levels of arsenic in drinking water, the likelihood of an earthquake at Diablo Canyon, and the probable consequences of hundred-year flooding of the Mississippi River on St. Louis. And there are corresponding questions of policy that depend on the answers we discover to these questions. But neither the science nor the policy design can be done by solitary geniuses working in their garages; instead, organizations must be tasked to do the work. These include universities, research institutes, and think tanks. And there are well understood institutional pressures, both internal and external, that drive the knowledge production enterprise off center. So here is the critical epistemic question: how can we assure ourselves that these institutions will arrive at scientifically justified conclusions without crippling distortions created by the funding and career environments in which they are lodged?

Both science (knowledge creation) and policy (action planning) need to be conducted in a way that is fundamentally guided by the data that the world presents to us and the most honest theorizing we can do in order to make sense of the causal infrastructure of those data. We don't want the scientists and engineers who evaluate the safety of chemical plants to be in the pockets of the chemical companies, and we don't want the land-use planning commission in Mississippi River cities to be beholden to real estate developers. Instead, we want neutral, disinterested, fact-driven research and policy design.

But here is the thing: it is flatly impossible to detach the institutions of knowledge and policy from the external realities within which they exist. And those realities include the facts of interests and influence. So it is crucial that we do a better job of embedding these enterprises within institutional and normative systems which honestly confront the distortions and find ways of offsetting them. Universities have well developed standards governing conflict of interest and commitment, and this is a good start. The academic ideals of insulating one's conclusions from the interests that support the research is another strand of objectivity. And the responsibility of stewards of universities -- trustees, presidents, provosts, deans -- to protect the academic independence of the faculty of their institution is a third.

The NYT article illustrates yet another important counterbalance to the workings of interest and influence: the ability of a free press to "connect the dots" and to uncover the distorting influence of power and resource that permit privileged entities to advance their interests through the distortion of science and policy. Uncovering hidden forms of influence on science and policy is one of the most important functions of critical journalism, whether in the classic efforts of I. F. Stone or in the most recent work by Lipton, Williams, and Confessore.

None of this is a guarantee of objectivity and neutrality, but it takes us in the right direction.

(Here are earlier posts on the importance and difficulty of "connecting the dots" between a set of economic or political interests and a set of scientific and policy findings; link, link.)

Tuesday, January 17, 2012

Sociology of knowledge: Camic, Gross and Lamont


The sociology of knowledge has received a new burst of energy in the past few years, with quite a bit of encouragement and innovation coming from Science, Technology and Society studies (STS).  (STS overlaps substantially with the SSK research tradition described briefly in an earlier post.)  Charles Camic and Neil Gross have made very substantial contributions in the past few years, with special focus on the knowledge activities associated with the humanities and social sciences.  (Gross's intellectual sociology of Richard Rorty is discussed here.)

So what is going on in this field today?  Camic, Gross, and Lamont, Social Knowledge in the Making, offers a genuinely pathbreaking collection of articles on different aspects of "social knowledge practices".  The editors' introduction to the volume does an excellent job of laying out the issues that current sociology of knowledge needs to confront.  They illustrate very clearly the differences in perspective associated with traditional intellectual history (which they describe as "traditional approach to social knowledge"; TASK), reductionist sociology of knowledge (attempting to link social conditions to specific set of ideas), and the science studies approach, which focuses a great deal of attention on the specific knowledge practices through which a community constructs and furthers a body of knowledge.

The editors make the point that the STS framework (and the SSK approach) is largely focused on the social practices connected with the natural and biological sciences -- laboratories, graduate schools, journals, conferences. And they argue that the fields of knowledge production involved in social knowledge are both important and distinctive.  (They are distinctive for at least three reasons: social knowledge is reflexive, the data must be gathered from subjective participants, and there are powerful interests in play that are pertinent to various formulations of social knowledge.)  So it is timely to pay equally close attention to the practices and institutions through which economics, philosophy, sociology, or Asian Studies frame and construct knowledge.  This volume attempts to give a number of rigorous examples in different areas of the social knowledge domains of that kind of empirical-sociological research.

Here are a few premises of the editors' approach to the problem:
By "social knowledge" we mean, in the first instance, descriptive informaton and analytical statements about the actions, behaviors, subjective states, and capacities of human beings and/or about the properties and processes of the aggregate or collective units -- the groups, networks, markets, organizations, and so on -- where these human agents are situated. (kl 78)
They also include in their definition of social knowledge the ways of knowledge making:
... the technologies and tools of knowledge making -- that is, the epistemic principles, cognitive schemata, theoretical models, conceptual artifacts, technical instruments, methodological procedures, tacit understandings, and material devices by which descriptive and normative statements about the social world are produced, assessed, represented, communicated, and preserved. (kl 78)
Key to their approach is to engage in detailed studies of the social practices associated with knowledge production.  Here is how they define a social practice:
We define "practices" as the ensembles of patterned activities -- the "modes of working and doing," in Amsterdamska's words -- by which human beings confront and structure the situated tasks with which they are engaged.  These activities may be intentional or unintentional, interpersonally cooperative or antagonistic, but they are inherently multifaceted, woven of cognitive, emotional, semiotic, appreciative, normative, and material components, which carry different valences in different contexts. (kl 122)
The goal of this research effort is to do for the social sciences and humanities what the STS/SSK researchers have done for the natural sciences.  This tradition has ...
shifted scholarly attention away from science as a finished product in the temple of human knowledge and toward the study of the multiple multilayered and multisited practices involved during the long hours when future kernels of scientific knowledge are still in the making. (kl 152)
Here is one of the core observations that the editors draw from the research contributions to the volume:
One of these themes is that social knowledge practices are multiplex, composed of many different aspects, elements, and features, which may or may not work in concert. Surveying the broad terrain mapped across the different chapters, we see, for example, the transitory practices of a short-lived research consortium as well as knowledge practices that endure for generations across many disciplines and institutions... (kl 338)
At site after site, heterogeneous social knowledge practices occur in tandem, layered upon one another, looping around and through each another, interweaving and branching, sometimes pulling in the same directions, sometimes in contrary directions. (kl 353)
So how can this research goal be carried out in practice?  Here is how Andrew Abbott pursues some of these questions in his contribution to the volume in an essay that investigates in detail how historians have used libraries in their research:
I have two major aims in this chapter. The first is empirical. I want to recover the practices, communities, and institutions of library researchers and their libraries in the twentieth century. There is at present almost no synthetic writing about this topic, and I aim to fill that gap. This empirical investigation points to a second more theoretical one.  There turns out to be a longstanding debate between librarians and disciplinary scholars over the proper means to create, store, and access the many forms of knowledge found in libraries. By tracing the evolution of this debate, I create a theoretical context for current debates about library research. (kl 581)
One thing I find interesting in reading this work is the absence of the philosophy of science as one of the reflective areas of research through which the knowledge process is examined.  Thomas Kuhn is mentioned as an intellectual founder of the historical-sociological approach to the problem of scientific knowledge; but the vibrant discipline of the philosophy of science is not mentioned by any of the contributors.  This seems to be a lost opportunity, since philosophers too are trying to make sense of the processes, procedures, and norms of the sciences along the way towards an interpretation of philosophical ideas such as truth and objectivity in knowledge.  It would be highly interesting to see a careful study of the development of post-positivist philosophy of science (from Peter Achinstein, Hilary Putnam, and Bas van Fraassen to the present day, let's say), by a sociologist who is willing to take the trouble to carefully examine the doctrines, schools, graduate programs, journals, associations, and dominant ideas that have evolved in the past half century within philosophy.

Tandem with this absence of the philosophy of science is an avoidance of epistemic concepts like "validity," "approximate truth," or "widening understanding of how the social world works."  The impression given by this volume, anyway, is that the task of the sociology of knowledge is solely restricted to examination of the practices and material conditions through which systems of belief about the social world are formed, without a concomitant interest in evaluating the success of the enterprise at establishing some of the facts of how the world works.  This impression is born out in the closing paragraphs of Camic's entry on "Knowledge, Sociology of" in the International Encyclopedia of the Social and Behavioral Sciences. Referring essentially to the approach taken by contributors to Social Knowledge in the Making, Camic writes:
This second approach focuses the sociology of knowledge mainly on men and women who specialize in the production of ideas and on the particular social processes by which their ideas emerge and develop—a move that, in effect, transforms the field into a sociology of ideas. This perspective has tended to reject the core assumptions of the older sociology of knowledge, building instead on schol- arship that argues that sociocultural processes are as much internal to the content of ideas as they are external (Bloor 1976, Shapin 1992), that the meanings of ideas are only understandable to an investigator after careful contextual reconstruction (Skinner 1969), and that local, micro-level settings are often the main sites for the development of ideas (Geertz 1983, Whitley 1984). Like the broad-constructionist ap- proach, this narrow-constructionist perspective pre- sently provides a foundation for several lines of empirical research (see Camic and Gross 2000). No forecast can yet be made, however, as to which approach, if either, will rescue the sociology of knowledge from its traditionally marginal position in the discipline of sociology. (8146)
This excerpt too emphasizes the internal practices of the various knowledge communities, rather than the likelihood that the product of knowledge production is valid, veridical, or rationally supportable.

As I found in the earlier post on research communities, it seems that there needs to be more communication and mutual learning between the sociology of science and the philosophy of science. Admittedly the two disciplines have different goals; but in the end, we would like to understand both aspects of the process of knowledge formation in a way that makes coherent sense: the concrete social practices and the cognitive merits of the results.  Otherwise we have no basis for diagnosing what went wrong with Soviet biology and Lysenkoism (depicted in the photo at top).

Saturday, June 25, 2011

Mental illness, big pharma and agent-based simulation


The New York Review of Books has an absorbing two-part piece by Marcia Angell on mental illness, psychiatry, and big pharma (link, link). (The NYRB Facebook page provides a good way of following the NYRB.)  Angell provides an in-depth discussion of books by Irving Kirsch, Robert Whitaker, and Daniel Carlat. There has been an explosion in the numbers of patients diagnosed with a list of mental disorders, and there has been an explosion in the profits associated with the drugs prescribed in treatment of these disorders as well.
It seems that Americans are in the midst of a raging epidemic of mental illness, at least as judged by the increase in the numbers treated for it. The tally of those who are so disabled by mental disorders that they qualify for Supplemental Security Income (SSI) or Social Security Disability Insurance (SSDI) increased nearly two and a half times between 1987 and 2007—from one in 184 Americans to one in seventy-six. For children, the rise is even more startling—a thirty-five-fold increase in the same two decades. Mental illness is now the leading cause of disability in children, well ahead of physical disabilities like cerebral palsy or Down syndrome, for which the federal programs were created. (Angell, part 1)
What is going on here? Is the prevalence of mental illness really that high and still climbing? Particularly if these disorders are biologically determined and not a result of environmental influences, is it plausible to suppose that such an increase is real? Or are we learning to recognize and diagnose mental disorders that were always there? On the other hand, are we simply expanding the criteria for mental illness so that nearly everyone has one? And what about the drugs that are now the mainstay of treatment? Do they work? If they do, shouldn’t we expect the prevalence of mental illness to be declining, not rising? (Angell, part 1)
To oversimplify, the thrust of several of these books is that the psychoactive drugs created the mental illnesses through the profit incentives and strategies of big pharma, rather than the diseases creating the drugs (through research and development aimed at treating the diseases).
This is over-simple, of course, since no one would question that mental illnesses exist prior to drugs. But the explosion of treated disorders like depression, anxiety, sleep disorders, and attention deficit disorder in children -- the "epidemic" to which Angell refers -- seems to conform to the reverse order. Deliberate strategies of marketing, influence on physicians, and influence on guiding medical documents such as the DSM seem to have produced a much larger patient base in specific mental disorders, with large profits accruing to pharma as a consequence.  (Ian Hacking looks at the degree to which mental illnesses are socially constructed in The Social Construction of What?.)

Here is the main thrust of the interpretation offered by the books that Angell reviews:
First, [the authors] agree on the disturbing extent to which the companies that sell psychoactive drugs—through various forms of marketing, both legal and illegal, and what many people would describe as bribery—have come to determine what constitutes a mental illness and how the disorders should be diagnosed and treated. (Angell, part 1)
A couple of pieces of evidence are especially pertinent in support of this telling of the story. One is the observation that psychiatrists as a profession are the largest beneficiaries of funding by pharma, by a large margin.
As psychiatry became a drug-intensive specialty, the pharmaceutical industry was quick to see the advantages of forming an alliance with the psychiatric profession. Drug companies began to lavish attention and largesse on psychiatrists, both individually and collectively, directly and indirectly. They showered gifts and free samples on practicing psychiatrists, hired them as consultants and speakers, bought them meals, helped pay for them to attend conferences, and supplied them with “educational” materials. When Minnesota and Vermont implemented “sunshine laws” that require drug companies to report all payments to doctors, psychiatrists were found to receive more money than physicians in any other specialty. The pharmaceutical industry also subsidizes meetings of the APA and other psychiatric conferences. About a fifth of APA funding now comes from drug companies.
Drug companies are particularly eager to win over faculty psychiatrists at prestigious academic medical centers. Called “key opinion leaders” (KOLs) by the industry, these are the people who through their writing and teaching influence how mental illness will be diagnosed and treated. They also publish much of the clinical research on drugs and, most importantly, largely determine the content of the DSM. In a sense, they are the best sales force the industry could have, and are worth every cent spent on them. Of the 170 contributors to the current version of the DSM (the DSM-IV-TR), almost all of whom would be described as KOLs, ninety-five had financial ties to drug companies, including all of the contributors to the sections on mood disorders and schizophrenia.  (Angell, part 2)
A second piece of evidence is a recounting of the drafting of the Diagnostic and Statistical Manual of Mental Disorders (DSM) through five editions, especially the third edition. In each case there is a strong suggestion of swaying of medical and scientific opinion through financial incentives.
These efforts to enhance the status of psychiatry were undertaken deliberately. The APA was then working on the third edition of the DSM, which provides diagnostic criteria for all mental disorders. The president of the APA had appointed Robert Spitzer, a much-admired professor of psychiatry at Columbia University, to head the task force overseeing the project. The first two editions, published in 1952 and 1968, reflected the Freudian view of mental illness and were little known outside the profession. Spitzer set out to make the DSM-III something quite different. He promised that it would be “a defense of the medical model as applied to psychiatric problems,” and the president of the APA in 1977, Jack Weinberg, said it would “clarify to anyone who may be in doubt that we regard psychiatry as a specialty of medicine.”
When Spitzer’s DSM-III was published in 1980, it contained 265 diagnoses (up from 182 in the previous edition), and it came into nearly universal use, not only by psychiatrists, but by insurance companies, hospitals, courts, prisons, schools, researchers, government agencies, and the rest of the medical profession. Its main goal was to bring consistency (usually referred to as “reliability”) to psychiatric diagnosis, that is, to ensure that psychiatrists who saw the same patient would agree on the diagnosis. To do that, each diagnosis was defined by a list of symptoms, with numerical thresholds. For example, having at least five of nine particular symptoms got you a full-fledged diagnosis of a major depressive episode within the broad category of “mood disorders.” But there was another goal—to justify the use of psychoactive drugs. The president of the APA last year, Carol Bernstein, in effect acknowledged that. “It became necessary in the 1970s,” she wrote, “to facilitate diagnostic agreement among clinicians, scientists, and regulatory authorities given the need to match patients with newly emerging pharmacologic treatments.”  (Angell, part 2)
Another element of the strategy used by the drug companies to promote their products, according to these authors, is the selective way that clinical studies are used in order to establish the safety and effectiveness of a given psychoactive drug:
For obvious reasons, drug companies make very sure that their positive studies are published in medical journals and doctors know about them, while the negative ones often languish unseen within the FDA, which regards them as proprietary and therefore confidential. This practice greatly biases the medical literature, medical education, and treatment decisions. (Angell, part 1)
What this story made me think of was ... slime molds. Here's what I mean. Japanese researchers have discovered that certain examples of optimizing processes can be simulated with slime molds and food supplies distributed across space. Here is an example of this research in the context of rail networks: the researchers found that a colony of slime mold essentially reproduces the configuration of existing rail networks when food is distributed in a configuration mirroring major cities (Tero et al 2010; link, link). Here is the experiment based on the configuration of cities around Tokyo:



After about a day of growth, the slime mold has established a network of tunnels connecting the food supplies, and this network looks strikingly similar to the configuration of Japanese railroads in the region.

So here's the question for consideration here: what if we attempted to model the system of population, disease, and the pharmaceutical industry by representing pharma as the slime organism and the disease space as a set of disease populations with different profitability characteristics? Would we see a major concentration of pharma slime around a few high-frequency, high profit disease-drug pairs? Would we see substantial underinvestment in pharma slime on low frequency low profit "orphan" disease populations? And would we see hyper-concentrations around diseases whose incidence is responsive to marketing and diagnostic standards?

I'm just speculating here, but I'm guessing that a Petri dish designed with these characteristics would produce the outcome described in the books included in the Angell reviews: a hyper-concentration of the slime organism around the "plastic" diseases that display positive feedback from marketing to incidence.  Essentially the model would suggest that the pharma industry "grows" into the space of emerging diseases, making investments in research and marketing that allow for growth of revenues around the disease segments of the population.

I suppose that this thought experiment simply supports a dismal but familiar finding: that profit-maximizing firms will aggressively seek out new sources of profits; that they will be particularly interested in opportunities where the possibility exists of strategically increasing the demand market; and that they will find creative ways of inducing other actors to behave in ways that enhance their business interests. Unfortunately, in this case the business optimal outcome seems to have very negative consequences for public health. And it seems to cast some doubt on the ability of professional ethics and conflict of interest policies to keep the medical profession as a whole on the track of placing the patient's health as the highest priority.

(I think this thought experiment could be recast as an agent-based simulation, with similar results.)

Thursday, December 17, 2009

Merton's sociology of science



The organized study of "science" as an epistemic practice and a knowledge product has taken at least three major forms in the past century: the philosophy of science, the history of science, and the sociology of science.  Philosophers have been primarily interested in the logic of scientific inquiry and the rational force of scientific knowledge.  Historians have been interested in the circumstances, both external and internal, through which important periods of the growth of scientific knowledge have occurred -- the Newtonian revolution, the Darwinian revolution, the "discovery" of cold fusion (above).  And sociologists have been interested in examining the norms and organizations through which "science" is practiced -- how young scientists are trained, how collaboration and competition work within a scientific discipline or a laboratory, how results are assessed and communicated.

And because the intellectual frameworks within which philosophers, historians, and sociologists have been educated differ substantially, these meta-disciplines of the study of science are significantly different as well.  The philosophers are largely interested in the quality of the product -- the rational force of a given body of scientific knowledge.  The historians are interested in the contingencies of development of a given field.  And the sociologists are interested in the social processes that lead to the creation of a body of scientific knowledge; they are inclined to "bracket" the epistemic standing or truth-value of the theories and hypotheses that a tradition has produced.

Robert Merton was one of the giants of American sociology.  One of his core contributions had to do with his efforts to define the subject matter and methodology of the sociology of science.  A volume of Merton's essays from the 1930s through 1960s on the sociology of science appeared in 1971, The Sociology of Science: Theoretical and Empirical Investigations, and these essays are worth re-reading today.  Here are some of Merton's formulations of the task of the sociology of science in "The Neglect of the Sociology of Science" (1952):
Numerous works ... have variously dealt with one or another part of the subject [of the sociology of science].  But these ... have not examined the linkage between science and social structure by means of a conceptual framework that has proved effective in other branches of sociology. (210)
Among current introductory textbooks in sociology ... all deal at length with the institutions of family, state, and economy, many with the institution of religion, but very few indeed with science as a major institution in modern society. (211)
Unlike the pattern in solidly established disciplines, in the sociology of science, facts are typically divorced from systematic theory.  Empirical observation and hypothesis do not provide mutual assistance.  Not having that direct bearing on a body of theory which makes for cumulative knowledge, the empirical studies that have been made, from time to time, by natural scientists have resulted in a thin scattering of unconnected findings rather than a chain of closely linked findings. (212-13)
So the goal of the sociology of science is to examine the linkage between science and social structure using the "conceptual frameworks" of sociology.  The sociology of science needs to be based on empirical observation -- i.e. it cannot be a purely conceptual discipline.  But it must possess an appropriate framework of sociological theory within the context of which empirical observations of scientific practice can be explained.

Several ideas were particularly important in Merton's efforts to conceptualize the processes of science:
  • the importance of discovering the norms that underlay the research and thinking of scientists in a given field (the ethos of science); ("the emotionally toned complex of rules, prescriptions, mores, beliefs, values and presuppositions that are held to be binding upon the scientist")
  • the internal social structure of various scientific disciplines (training, communication, information flow, evaluation)
  • the incentives that exist within the scientific disciplines that constitute the driving force for scientists to aggressively pursue publishable results; the reward system.  How do the imperatives of the ethos and the institutions of science come together to determine the patterns of behavior of the individual working scientist?  
One of Merton's key methodological contributions was the idea that it was possible to observe and measure the institutions of science through careful empirical examination of the biographies, journals, and other objective markers of scientific activity. (This is what he refers to as the conceptual framework of sociology.)  He repeatedly attempts to quantify and measure the activities of science -- publication rates, inventions, numbers of scientists in a field, and so forth.  For example, in "Changing Foci of Interest in the Sciences and Technology" (1938) he attempts to estimate the pattern of shifting scientific interest in England over the period of 1665-1702 by counting the numbers of articles to be published in various areas of science (tables 3-4). He finds that the physical and formal sciences fall in frequency during this time period, while the life sciences rise significantly (201).  How should we explain this shift in the interests of the scientific community?  Merton advocates a sociological cause.  Referring back to Rickert and Weber, he argues that this shift is likely to be linked to the broader societal interests of the time period:
Scientists often choose problems for investigation that are vitally linked with major values and interests of the time.  Much of this study will examine some of the extra-scientific elements which significantly influenced, if they did not wholly determine, the foci of scientific interest. (203)
Another of Merton's key ideas is the role of the reward system of science, which he takes to be the motor of scientific change:
Like other institutions, the institution of science has developed an elaborate system for allocating rewards to those who variously live up to its norms.... The evolution of this system has been the work of centuries, and it will of course never be finished.  (297)
And he finds that this reward system gives great weight to originality and priority -- which leads to the recurring phenomena of priority disputes, fraud, and plagiarism in science (309).  And it leads as well to the phenomenon of multiple discovery by independent researchers:
The pages of the history of science record thousands of instances of similar discoveries having been made by scientists working independently of one another.  Sometimes the discoveries are simultaneous or almost so; sometimes a scientist will make anew a discovery which, unknown to him, somebody else had made years before.  Such occurrences suggest that discoveries become virtually inevitable when prerequisite kinds of knowledge and tools accumulate in man's cultural store and when the attention of an appreciable number of investigators becomes focused on a problem, by emerging social needs, by developments internal to the science, or by both. (371)
A final topic of interest in Merton's sociology of science is his treatment of "peer review".  Here is how he describes this part of the institutions of science in "Institutionalized Patterns of Evaluation in Science" (1971):
The referee system in science involves the systematic use of judges to assess the acceptability of manuscripts submitted for publication.  The referee is thus an example of status judges who are charged with evaluating the quality of role-performances in a social system.  They are found in every institutional sphere. (460)
So we might encapsulate Merton's intellectual framework for the sociology of science in a few basic ideas: the sociologist needs to find ways of observing scientific practice empirically; the conduct of science is driven by the values that the institutions of science inculcate and enforce; the incentives created by the scientific institutions shape and motivate the behavior of scientists; and the product of science is the result of the constrained activities of scientists shaped and motivated in these particular ways.  So the sociologist needs to discover and document the values, he/she needs to uncover the evaluation mechanisms, and he/she needs to discover in detail how innovations and theories have emerged in specific research environments.

What this description leaves out from a contemporary perspective might include:
  • analysis of social networks of collaboration and communication among scientists
  • analysis of the institutions of training through which scientists learn their craft
  • content analysis of the results of scientific inquiry -- recurring features of theory and explanation within specific research traditions
(Trevor Pinch is an important contemporary contributor to current sociology of science and is one of the editors of the 1995 volume, Handbook of Science and Technology Studies. Here is a link to his syllabus for a seminar on the sociology of science that indicates how he conceptualizes the discipline.)

Sunday, November 2, 2008

Are there "social kinds"?

Philosophers of science sometimes define the idea of a natural kind as "a group of things that share a fundamental set of causal properties." Examples might be "gold," "metal," and "protein molecule." And some philosophers assume that scientific realism means being realist about natural kinds. Do the typical concepts used in the social sciences succeed in identifying a social analog to natural kinds, which might be referred to as "social kinds"? And if not, is it possible to be realist about the social world but anti-realist with respect to "social kinds"?

First, what is involved in being “realist” in connection with the historical and human sciences? It is to assert several independent things: first, that there is the possibility of (fallibly) objective knowledge of social facts; second, that there are “social facts” to be known – that is, there are some mind- or interpretation-independent things that happen and can be the subject of knowledge; and third (questionably), that there are categories of higher-level social entities that “really” exist in the way that some philosophers say that natural kinds exist. It is entirely defensible to be a scientific realist in the social sciences, and I want to support the first two ideas but to argue against the third.

Concepts are of course essential to social knowledge. The heart of social inquiry has to do with coming up with concepts that allow us to better understand social reality: for example, racism, patterns of behavior, free market, class consciousness, ethnic identities. Theory formation in the social sciences largely consists of the task of constructing concepts and categories that capture groups of social phenomena for the purpose of analysis. But even the most successful social concepts do not identify groups of phenomena that could be called a "social kind." High-level social concepts that serve to pick out groups of social phenomena—states, riots, property systems—generally do not refer to causally homogeneous bodies of social phenomena; instead, each of these is composed of individual social formations with their own history and circumstances. There is no uniform causal constitution that underlies all states or riots. The philosophical notions of “family resemblance” and “cluster concepts” serve better to characterize these high-level social concepts than does “natural kind”.

Examples of what might have been thought to be social kinds might include concepts such as these: proletariat, underclass resentment, revolutionary situation, racism; liberal representative states; fascism; feudalism; bureaucratic state. But I hold that these are not kinds in the strong sense that philosophers of the natural sciences have in mind. Rather, they are plastic, variable, opportunistic, individually specific instantiations across a variety of human contexts. We need to be able to identify some topics of interest, so we need language and concepts; but we must avoid reifying the concepts and thinking they refer to some underlying discoverable essence. (Think of how Chuck Tilly conceptualizes riot, rebellion, and resistance in terms of “contentious politics.” Rightly, he avoids the idea that there is one common thing going on in these instances across time, history, and place; his goal is to identify a medium-sized body of causal mechanisms that bundle together in various contexts to give rise to one signature of contention or another.)

The discovery of causal processes is essential to social explanation -- not the discovery of high-level uniform categories of social events or structures. We explain social outcomes best when we can uncover the causal mechanisms that gave rise to them. However, most social ensembles are the result of multiple causal mechanisms, and their natures are not common, simple, or invariant. “States” embody mechanisms of social control. But as Tolstoy said about unhappy families, every state manages its contention in somewhat different ways. So we can’t and shouldn’t expect common causal properties across the class of “states”. And this is directly relevant to the central point here: the "state" is not a social kind, and there is no simple theory that encapsulates its causal properties.

This approach has specific implications for the conduct of the social sciences. For example, political science and the study of different types of states: we can identify common mechanisms, sub-institutions, building blocks, etc., that recur in different political systems. And we can offer causal explanations of specific states in particular historical circumstances -- for example, the Brazilian state in the 1990s. But we cannot produce strong generalizations about “states” or even particular kinds of states -- for example, “developing states”. Or at least, the generalizations we find are weak and exception-laden. Rather, we must build up our explanations from the component mechanisms and institutions found in the particular cases.

So here is a moderate form of scientific realism that is well suited to the nature of the social world: be realist about social mechanisms but not about social kinds. Be realist and empiricist in epistemology: we can arrive at rationally justified beliefs about social mechanisms. And be a skeptic or nominalist about social kinds. There are no macro or molar-level social kinds.

Friday, May 16, 2008

Social science history and historical social science


Social science methods and historical explanation seem to come together in several different ways; what can we say about the differences of approach between “history using the tools of the social sciences” and “social science research that pays close attention to history”?

E. P. Thompson treats the making of the English working class. His work is multi-faceted. He gives treatment of workingmen’s organizations and publications; churches and pastors; riots and chants; petitions to parliament; and much else. The story is historical in several respects: it provides an account of change over time and it engages in detailed and fine-grained description of specific circumstances in the past. Is Thompson attempting to explain something? Perhaps it is more accurate to say that his aim is to describe this extended, multi-location, multi-group process of “making”, along with some sense of the circumstances and features of agency that brought this “class” into being. And he goes out of his way to emphasize the contingency of the story that he tells: this “class” could have taken a very different shape, depending on altered circumstances and agency along the way. His is as much like the work of a biographer, detailing the development of personality, the contingencies of personal history, the formation of character, and the actions of the mature person.

Charles Tilly treats the development of contentious politics in France over three centuries. His account too is “historical”: it describes the development and diversity of contentious politics in France through revolution and periods of quiet. His account too is attentive to difference; he emphasizes the many ways in which French contentious “underclass” politics varied across time and across region. The politics of workers in Paris were quite different from those of the winemakers of the Vendée. But Tilly’s account is deliberately sociological and theoretical. The goal of his study is to discover causes; to test a few theoretical hypotheses about mobilization; and to use the “data” of French working class history as a basis for testing and evaluating sociological theory.

Each of these examples is a major intellectual contribution; each contributes to our historical understanding; each focuses on a historically situated working class. But the two oeuvres have substantial differences of orientation and feel. One is explicitly theoretical in its goals; the other is nuanced and descriptive. One aims at arriving at explanations; the other is interested in providing a qualitative understanding of the experience of ordinary men and women of the 18th and 19th centuries in rural England. One is historical social science, while the other is social science history.

So it is an important question within the philosophy of history, to articulate the difference between these two configurations of “social science” and “history.” How are the two genres distinguished? Are they differences of style, each embodying a complex of narrative and explanatory values? Are they at opposing ends of some sort of spectrum, ranging from descriptive to explanatory or concrete to abstract? Or are they actually logically different in some way—perhaps along the lines of the distinction between three conceptions of time described by William Sewell?

Perhaps most extremely, would we be right to consider excluding Tilly’s work from the domain of the “historical” and place it instead within the domain of social science, distinguished from other varieties of social science primarily by the fact that the data upon which it depends are facts about the past? In other words, is it possible to suggest that “historical social science” is not a variety of historical writing at all?

How might we characterize some of the differences between these two bodies of writing about the past? Do they constitute different paradigms, research frameworks, or forms of historical practice? Do they embody different complexes of assumptions about what to emphasize, what the standards of rigor are, what is required by way of description, detail, and fact; what is intended by way of explanation and understanding; the role that interpretation of the lived experience of agents plays; and so on?

Comparative historical social science is a particular instance of historical social science. There is a well-developed contemporary literature on the conceptual and methodological issues raised by comparative historical social science. And the participants in this literature generally seem to come down on the side of the “social science” conclusions rather than the “historical explanations” side of the debate. The goal of comparative social science is to assess causation, and to use knowledge of concrete historical cases as a source of evidence for evaluating causal theories. Examples include the explanation of social revolution (Theda Skocpol), the explanation of social contention (Charles Tilly), the explanation of economic development (R. Bin Wong, Philip Huang), the explanation of labor union politics (Howard Kimmeldorf).

Now let us turn the lens in the other direction and ask, in what ways do the contents of social science knowledge aid in the construction of historical knowledge? What is the role of theory and causal hypothesis in paradigm examples of historical knowledge? Virtually all historians would first insist: “Historical research cannot take the form of application of social science theory to the data. Rather, the historian’s task is to discover the particular and the grain of the materials in front of him. History is not the unfolding of theoretical premises and good historical knowledge does not result from deducing consequences from general social science theories.” That being conceded: are there forms of historical inquiry and knowledge that are importantly and rationally assisted by social science theory?

One variant of historical writing where social science theory is apparently pertinent is in the “causal narrative”. Historians are well served by appealing to social science theories of causal mechanisms in order to explain the transitions that they identify in their causal narratives. This is a logical point. And yet, it is strikingly difficult to find examples of leading historians who make use of social science theory in this way. Philip Huang is an example of a professional historian who makes substantial use of social science theory and concepts; Simon Schama is an example of a historian who is averse to this use. More commonly, the authors who provide causal narratives informed by social science theory are themselves sociologists or other social scientists (Skocpol, Tilly, Wolf, Paige).

It seems from some of these scattered observations, that there is indeed a significant difference between social science history and historical social science. The explanatory goals appear to be different, and the methods of reasoning and standards of rigor and adequacy seem to be distinct as well. So the question of how the disciplinary differences fit together is one that demands continued scrutiny.